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Conjugated Linoleic Acid (CLA) |
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Lipid abnormalities |
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Conjugated Linoleic Acid (CLA) is a group of substances that resemble fatty acids. Each of the different types of CLA is referred to as an “isomer” or variation of CLA. A process that has some similarities to the one that produces trans fatty acids produces CLAs. CLAs are metabolized in perosixomes. Presence of CD 16:2 indicate Peroxisomal oxidation.
In animal models, CLA may decrease the formation of fatty acid streaks that are the precursor of atherosclerosis. In rabbits, it may cause regression of lesions due to high cholesterol. Some studies have suggested that CLA may inhibit cancer cell growth.
However, before jumping to eat CLA, one must remember that many toxic substances inhibit cancer or heart disease... but cause other problems in humans. Humans are quite different from animals (some humans may be rats, but rats are not human). CLA is found in some milk and cheese fats, and small amounts are probably not harmful. However, eating large amounts of CLA may have unforeseen effects.
Our advice: wait until others volunteer for experiments, and be sure you get paid well and have excellent health coverage before you participate in experiments with new drugs or substances like CLA.
Website for CLA references: http://www.wisc.edu/fri/clarefs.htm
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© 1998 Edward
Siguel. All rights reserved |
modified 1/15/00 |