Seminar
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Edward Siguel, MD PhD |
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PO Box 10187, Gaithersburg MD 20898-0187 Dear Colleague: I am available to talk on the impact of essential fatty acids (EFAs), EFA abnormalities, and diet on cardiovascular disease and cholesterol levels. In 1993, I published a paper showing that trans fatty acids (TFAs) are a major risk factor in coronary artery disease (CAD). At the American College of Cardiology in Atlanta (3/94), I presented a poster showing that fatty acid profiles are a major determinant of HDL/ Total cholesterol. This poster was selected, among thousands, to be announced at a Press Conference highlighting recent advances in cardiac medicine called by the American College of Cardiology on 3/14/94. In the fall of 1994, I published a paper in Metabolism identifying the specific fatty acid profiles associated with CAD and HDL/ Total Cholesterol. This research was widely reported in the news media, including The New York Times, Time magazine, The Boston Herald, The Chicago Tribune, and numerous radio stations, TV, and magazines. I have shown that patients with chronic gastrointestinal disease have severe fatty acid abnormalities. I identified a new relationship between PUFAs and ratios of Total/HDL cholesterol and written extensively about the diagnosis of fatty acid abnormalities and deficiencies. My research, based on my database of patients, subjects, and subjects from the Framingham Heart Study, identifies new types of fatty acid metabolic disorders, including deficiencies and abnormalities of EFAs. I have found that EFA deficiency is a common problem in the US. Among the many "corollaries" of my research, I propose that very low fat diets are likely to cause EFA abnormalities and lead to hyperlipidemia and CAD. I propose that the USDA food "pyramid" is misleading because it encourages diets low in EFAs. I have developed a method to measure EFAs and diagnose disorders of fatty acid metabolism which is about 10 times more sensitive than previous methods. I have evaluated fatty acid profiles in TPN patients and patients with chronic intestinal disorders, obesity, neurological disease, cystic fibrosis, and other conditions (for a brief description of results, see the attached brochures and citations). Possible topics (technical level is tailored to each audience):
Similar topics are available for professional and community groups. The talks for professionals (physicians, nurses, dietitians and other health professionals) describe medical issues in greater detail. If you would like me to give a talk, please contact us. Sincerely, |
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© 1998 Edward Siguel. All rights reserved |
modified 9/17/98 |