Siguel's Publications and Articles (annotated)
|
|
|
Search for listing of Dr. Siguel's publications -- abstracts are available through the National Library of Science's PubMed service. |
Here is a selected listing of publications and articles of interest about EFAs. If you find errors, please contact us.
Siguel, E. Letter to
the Editor regarding n-3 Fatty Acids and the Risk of Sudden Death. New
England Journal of Medicine 2002; 347(7):531.
Siguel, E. Clinical Impact of Methodological
Issues in the Diagnosis of Deficiencies and Abnormalities of Essential Fats. Journal
of Clinical Ligand Assay 2000; 23:112–121.
Siguel, E. Deficiencies and Abnormalities of
Essential Fats in Gastrointestinal and Coronary Artery Disease. Journal of
Clinical Ligand Assay 2000; 23:104–111.
Siguel E. Re: Anticipation in Crohn's disease
may be influenced by gender and ethnicity of the transmitting parent. Am J
Gastroenterol. 1999 Jul;94(7):1996.
Siguel E. Identification and quantification
of fatty acids. JPEN J Parenter Enteral Nutr. 1998 Nov-Dec;22(6):401-2.
Siguel E. Diagnosing Essential Fatty Acid
Deficiency. Circulation. 1998 Jun 30; 97(25): 2580-2583.
Siguel, E. "Low-fat, high carbohydrate
diets also reduce high-density lipoprotein (HDL) cholesterol levels and raise
fasting levels of triglycerides." BioMedicina, January 1998; 1(1):
9.
Siguel EN. Dietary modulation of
omega-3/omega-6 polyunsaturated fatty acid ratios in patients with breast
cancer. J Natl Cancer Inst. 1998 Apr 15; 90(8): 629-631.
Siguel E. Low- and High-fat, Peptide-based
Diets in Adolescents with Active Crohn's Disease. J Parenter Enteral Nutr
1997;21(5):304.
Siguel, E.
Dietary Fat: How Low Can or Should You Go? Abstracts, Am. Oil.
Chemistry Society Annual Meeting 1997; INFORM,
1997:8, No7:714-717.
Siguel, E. Comments on Low Fat Diets and EFA Measurements. Circulation, 1997.
Siguel E. Essential fatty acid status in
patients. J Parenter Enteral Nutr. (JPEN ) 1997 Jul; 21(4): 243.
Siguel, E. The Essential
Fat Revolution: Part I, Nutrition and Essential Fatty Acids. Decision
Resources, Waltham, MA. December 12, 1997: 81-1 - 81-12.
Siguel, E. The Essential
Fat Revolution Part II, Implications for Food Design and Marketing. Decision
Resources, Waltham, MA. December 12, 1997:82-1 - 82-10.
Siguel, E. Introduccion al Metabolism de los
Acidos Grasos (Intr to Metab of Fatty Acids). MEDICO Interamericano,
1996/Vol 15 No12: 723-726.
Siguel, E.
Issues and Problems in the Design of Foods Rich in Essential Fatty
Acids. Lipid Technology, 8(4):81-86, 1996 (July).
Siguel E, Lerman, RH. Fatty Acid Patterns in
Patients with Chronic Intestinal Disease. Metabolism. 1996; 45(1):12-23.
(Jan)
Shows that EFA abnormalities are common in patients with Crohn's disease,
Cystic Fibrosis, and other similar conditions. Explains how to diagnose and
treat these abnormalities and implications for patient well-being.
Siguel, E. A new
relationship between PUFAs and TC/HDLC. Lipids, 1996; 31, S51-S56.
A new diagnosis and treatment approach to abnormal cholesterol ratios.
Siguel E. Dietary Sources of Long-Chain n-3
Polyunsaturated Fatty Acids. JAMA, 1996; 275:836.
Siguel E, Lerman RH. The effects of Low-Fat Diet on
Lipid Levels. JAMA, 1996; 275:759.
Discussion with other scientists of the dangers of low-fat diets.
Siguel E, Lerman RH, MacBeath, B. Low-Fat
Diets for Coronary Heart Disease: Perhaps, But Which One? JAMA, 1996:275:
1402-1403.
Discussion with other scientists of the dangers of low-fat diets. Case report.
56th Flax Institute of the US. Copies of 56th
Proceedings (1996)
[send $12 to Box 5051, University Station, North Dakota State University,
Fargo, ND, 58105. Tel (701) 231-7971.]
Articles on the use of flax. Diagnosis of EFA deficiency. Prevalance of EFA
abnormalities. Excellent review.
Siguel, E.
Diagnosis of EFA Abnormalities.
Proceedings of the 56th Flax Institute Meeting, Fargo, N. Dakota, 1996.
Siguel, E. Symposium on Measuring EFAs in
biological tissue. Proceedings Am. Oil. Chemistry Society annual meeting
1996.
EN Siguel, WMN Ratnayake. Trans Fatty Acid
Patterns in Patients with Demonstrated CAD. American Journal of Cardiology,
1995; 75:424.
Siguel E, Lerman RH, MacBeath, B. Very Low-Fat Diets for Coronary Heart
Disease: Perhaps, But Which One? JAMA,
1996:275: 1402-1403
Siguel, E. Erratum in JAMA 1996 Sep
25;276(12):954. Very low-fat diets for coronary heart-disease: perhaps, but
which one?
Siguel E. Does Linoleic acid contribute to
CAD? Am. J. Clin. Nutrition, 1995; 61:397-398 (let).
Siguel E, Lerman, RH. The role of EFAs: Reply
to the USDA. Am. J. Clin. Nutrition, 1995; 63:973-9.
Siguel EN. Essential
Fatty Acids in Health and Disease. 1994. EssentialFats LLC, PO Box 10187,
Gaithersburg MD 20898-0187. (book, list $39.95). Diagnosis and treatment of:
EFA abnormalities, abnormal lipids, diabetes, AIDS, Crohn's disease, cystic
fibrosis, heart disease, hypertension, and much more. Guidelines for patients
and physicians.
Siguel EN, Lerman, RH. Fatty Acid Patterns in
Patients With Angiographically Documented CAD. Metabolism 1994;
43:982-993.
Shows link between EFA abnormalities and heart disease + abnormal cholesterol
ratios.
Siguel EN. The role of EFAs in Health and
Disease. Nutrition Issue. Comprehensive
Therapy, 1994; 20(9):500-510.
Contains tables with prevalence of EFA deficiencies, percentiles, etc. Based on
200 subjects.
Siguel E. Essential and Trans Fatty Acid Metabolism in Health and
Disease. Nutrition Issue. Comprehensive
Therapy, 1994; 20(9):500-510. Review
Siguel E, Lerman, RH. Prevalence of Essential Fatty Acid
Deficiency in Patients with Chronic Gastrointestinal Disorders. Metabolism.
1996; 45(1):12-23. (Jan)
Siguel, E. interview, Spanish magazine. Que
Pasa, Nov 1994.
Siguel, EN. LA Marshall. Industry interview.
Researcher Sheds New Light on Fats. Natural Foods Merchandiser, 1994,
Sept: 75-76.
Siguel E, Lerman RH. The
role of EFAs: Dangers in the USDA dietary recommendations ("pyramid")
and in low fat diets. Am. J. Clin. Nutrition, 1994; 60:973-9.
Siguel EN, Lerman, RH. Trans fatty
acid patterns in patients with angiographically documented CAD. Am. J.
Cardiology 1993; 71:916-920.
Siguel, EN. Method And Apparatus for
Diagnosis of Fatty Acid or Lipid Abnormalities. U.S.
Patent No. 5075101, Issue date 12/24/91.
Patent to diagnose EFA abnormalities
London SJ, Sacks FM, Caesar J, Stampfer MJ,
Siguel, EN, Willett, WC. Fatty Acid Composition of Subcutaneous Adipose Tissue
and Diet among Postmenopausal US Women. Am.J.Clin.Nutr, 1991; 54:340-5.
Chee KM, Gong JX, Rees DMG, Meydani M.,
Ausman L, Johnson J, Siguel EN, Schaefer EJ Fatty Acid Content of Marine Oil
Capsules. Lipids 25, 1990:523-527.
Siguel EN, Schaefer EJ. Aging and Nutritional
Requirements of Essential Fatty Acids. In: Beare J, ed. Dietary Fats,
Champaign, Il. American Oil Chemists Society, Chapter 13. (1989).
Siguel E. Nutrient Charts: Essential
Fatty Acids. Nutr. Support Services. 8:24, Sept, 1988.
Warren SE, Siguel EN, Gervino E, Salzman, EW,
Smith, M, Silverman, KJ, Pasternak, RC. Effects of cod liver oil on plasma
lipids, eicosanoids, platelet aggregation, and exercise in stable angina
pectoris. J. Applied Cardiology, 3(4):227-236, 1988.
Siguel EN, Maclure, M. Relative enzyme
activity of unsaturated fatty acid metabolic pathways in humans, Metabolism,
36: 664-669, 1987.
Theory of metabolic pathway activity. Relationships among pathways. Reference
levels.
Siguel EN, Chee, KM, Gong J, Schaefer, EJ.
Criteria for EFA Deficiency in Plasma as assessed by Capillary Column
Gas-Liquid Chromatography. Clin Chem, 1987; 33:1869-1873.
Siguel EN, Blumberg JB, Caesar J. Monitoring
the Optimal Infusion of Intravenous Lipids: Detection of Essential Fatty Acid
Deficiency. Archives of Pathology and Laboratory Medicine. 110: 792-797,
1986.
Shows that patients fed soybean oil intravenously can do well.
Schaefer EJ, Rees DG, Siguel E. Nutrition, Lipoproteins, and
Atherosclerosis. Clin Nutrition, 5:99-111, 1986.
Meydani SN, Siguel E, Shapiro AC,
Blumberg JB. Fish Consumption and
Mortality from Coronary Heart Disease. New Engl J of Medicine, 313:822, 1985
(let).
Siguel
E. Type and frequency of Laboratory
Tests Required to Evaluate the Home TPN Patient. Nutr. Support Services,
4(8):16-18, 1984.
Siguel EN. Use of pumps for Enteral
Alimentation. Nutr. Support Services, 4(3):14-15, 1984.
For patients with Crohn’s disease, we explain the use of elemental diets and
pumps.
Siguel E. Use of Pumps for Enteral Alimentation: update. Nutr.
Sup. Serv. 6(2A):40-43, 1986.
Siguel E. Quality of Care and Quality of Life of Home Nutritional Support
Patients Viewpoint: Patients. Nutr.
Support Services, 4(8):35-41, 1984.
Siguel E. Acquired Disorders of Fatty Acid Metabolism. Am. Assoc. for the Adv. of Science Annual
Meeting, May, 1983 (Abstract).
Siguel E. The Impact of the Development of Community Mental Health Centers
on the Utilization of State and Mental Health Hospitals. PhD Thesis, U of Mich,
Ann Arbor, MI, 1974.
Siguel E. Isotopic steady-state requirements. Exp Mol Pathol 1975;
22(3):430-433.
Siguel E. Characteristics of Clients Admitted to Treatment for Cocaine
Abuse. NIDA Monogr., 13:201-10, 1977.
Siguel E, Sand S. Design
and analysis techniques for large data files: the CODAP system. Proc.
10th Annual Symposium on the Interface of Computers and Statistics, p 247-250.
National Bureau of Standards, Gaithersburg, MD, 1977. U.S. Gov. Print Off., No. 003-003-01908-9, Wash., DC, 1978.
Cost Effectiveness and Health. ORSA cost
effectiveness newsletter. csteffht
THE EPIDEMIOLOGY OF DRUG ABUSE: A NEW DATA
BASE, NEW TECHNIQUES AND NEW FINDINGS. Eduardo N. Siguel and William H.
Spillane, National Institute on Drug Abuse CODAP1
Siguel E. The Application of Computer Simulation to the Evaluation of Income
Maintenance Programs. Inst. of Electr.
and Electronic Eng, Trans. on Systems, Man and Cybernetics, October 1976:
695-698. IEEE.
Siguel E. Comments on Recent Advances in Molecular Pathology. Exp.Mol.
Pathol. 28(3):443-445, 1978.
Siguel E, Spillane WH. The Effect of Prior Treatment on Treatment
Success. Int.J.Addict. 13(5):797-805, 1978.
Ginzburg HM, Siguel E. Alcohol and Marijuana: Mixed Substance Abuse. Currents in Alcoholism, Vol IV: Psychiatric,
Psychological, Social and Epidemiological Studies. FA Seixas, Ed. Grune and Strotton, Inc. 1978.
Siguel E. Incidence of Heroin use for Voluntary and Involuntary Admissions
to Treatment. Chap. 2, Quantitative
Explorations in Drug Abuse Policy, Ed. by I. Leveson. Spectrum Publications, NY, 1980.
Merajver SD, Sheridan SP, Siguel
E. Theory of the Conformational Order
of Single Component Sphingomyelin Bilayers. J.Theoret.Biol.
93:737-755, 1981.
Siguel E. Triglycerides and HDL Cholesterol. N.Engl.J.Med.
304(7):424, 1981 (let).
Siguel E. Controversial Aspects of Nutrition. J.Parent.Ent. Nutr. 5:169-70, 1981 (let).
Siguel E. Cancerostatic Effect of Vegetarian Diets. Nutrition
and Cancer, 4:285-289, 1983.
We explained how vegetable diets may prevent or treat cancer, and provided a
new strategy for treatment of cancer.
Siguel E. Tube Displacement. Nutr. Support Services, 3(7):32, 1983
(let).
Siguel E, Spillane W. The Epidemiology of Drug Abuse: A New
Database, New Techniques and New Findings.
Proc. Social Statistics Sec. of the Am. Stat. Assoc. Meeting, l976.
Siguel E. A Qualitative Approach to Diabetes Treatment. Ann. meeting of the Society for Math
Biology, 1976.
Reports Prepared for the National
Institute on Drug Abuse Dealing with Planning and Evaluation of Drug Abuse
Programs and the Epidemiology of Drug Abuse, such as: Age at First Use for Heroin/Marijuana Users; Factors Associated
with Success in Treatment; Incidence of Heroin Abuse According to the Number of
Prior Treatment Experiences, Age, Race, Sex, SMSA; Tabulations of Drugs of
Abuse by Social/Demographic Variables; A Mathematical Model of Epidemics of
Drug Abuse; Budget, Planning, and Evaluations Plans for NIDA. (1975-1978).
Siguel E.
Cost Effectiveness and Health.
Cost Effectiveness Newsletter, ORSA Vol. 8 No. 2, 1973.
Multivariate Regression Analysis of
the Impact of the EEOC, OFCC and Justice Dept on Employment
Discrimination. OMB/ White House Task
Force. (1972).
Siguel E, Seubold F. Potential 10 Year Savings from HMO
Development Part 1, Health Maint Org.
Hearings before Subcom. on Public Health and Env, 92nd Congress, US Gov
Print Off, p. 92-95, 1972.
McClung N, Moeller J, Siguel E. Transfer Income Program Evaluation. The Urban Institute P# 950-3, 1971.
Siguel E, Schieber G. A Generalized Population Aging and
Disaggregation Technique. The Urban
Institute P#505:1, 1971.
Siguel E, et al. Estimates of Alternative Costs and Number of
Beneficiaries of Income Maintenance Programs.
Prepared for DHEW and US Congress, 1969-1971.
Articles that feature Siguel's work
Nash, J. Madeline. Is a Low-Fat Diet Risky? Time
magazine, September 5, 1994, 62.
Is too little fat bad for your health? Self
Magazine, Aug 94, 48.
Brody, Jane E. Study Suggests 2 Fatty Acids
May Help Keep Hearts Healthy. The New York Times, August 24, 1994.
Brandon, Richard, PhD. Is low-Fat Eating
Aging You? Longevity, September 1994.
Belleme J. Maximize Your Vitality. Natural
Health, September-October 1996, 44-46.
Blaste RA. Fat Chance. Allure,
September 1996, 176-178.
Marshall, Lisa Anne. What's an Essential
Fatty Acid? Delicious, February 1995, p.50-53.
Vaughan, Don. Fat-Free Diets Can Hurt Your
Heart. Your Health, November 29, 1994, 17-20, 108.
10% of Population May Have EFA Shortage. The
Nutrition Post, Fall 1994.
New Twist: Very Low-Fat Diet May Imperil
Heart. Chicago Tribune, August 24, 1994, p.3.
Ron Kotulak and Jon Van. Missing Link?; Preliminary Study Implicates
Shortage of Fatty Acids in Heart Disease.
Chicago Tribune, p. 4.
Steven Pratt, Low-Fat Double Backlash?
Whew. Advocates of Low-Fat Eating Dispute Conclusions Made by Study
Authors. Chicago Tribune, September 1, 1994, p. 6B.
Michael Lasalandra. Hub doc calls fat fine fare for heart Study
disputes diet tips for fighting coronaries.
Boston Herald, August 16,
1994, p. 3.
Low-fat diet questioned. Calgary
Herald, December 10, 1994, Pg. B6.
Clark, Amy Rosenbaum. Add essential fats to the fire; research on
fat's role in heart disease. Vegetarian Times Inc, December, 1994,
No. 208, P. 16.
Marshall, L A. What is an Essential Fatty Acid? Delicious,
February 1995, p.50-53.
Too little fat in your diet may be as
risky as too much. Environmental
Nutrition Inc, Feb 1995, 18(2):7.
Murphy, Kate. Is Fat Getting a Bad Rap? Business
Week, October 28, 1997.
The Atlanta Journal and
Constitution August 27, 1994: Science;
E; p 8. Study links low-fat diet, heart
disease Insufficient intake of 2 fatty acids cited
Better Nutrition for Today's Living
March, 1994; 56( 3): 24
Computer Applications
Siguel E. Two Articles in Medical Lab
Observer on how to set up a home page, use of Internet, 1995.
Siguel E. What PC to Buy in 1994; Two
Articles in Medical Lab Observer, 1994.
Siguel E. What PC to Buy in 1993; How to
Upgrade your Hard Drive; Time and Task Management in the Lab. Three articles in
Medical Lab Observer, 1993.
Siguel E. Casting your Net for Optimal
Networking. Medical Lab Observers, Feb 1992.
Siguel E. Personal Computers in the Lab: What
will the Future Bring? Medical Lab Observer, 1992:61-64.
Siguel E. How to Make a Fortune by Marketing
Good Laboratory Computers. Medical Lab Observer, May 1991, p.75-7.
Siguel E. The Future of Computer-Aided
Diagnosis in the Laboratory. Medical Lab Observer, Aug 1991, p.71-73.
Siguel E. Which PC to Buy Now. Medical Lab
Observer, Sept 1990, p.59-60.
Siguel E. Software Choices for Today. Medical
Lab Observer, Oct 1990, p.59-62.
Siguel E. How to Select Graphics Software. Medical
Lab Observer, May 1988, p 59-60.
Siguel E. Drawing a Bead on Graphics
Programs. Medical Lab Observer, June 1988, p 81-2.
Siguel E. A Shopping List for Buying PC's.
Four Parts: Hardware, Attachments, Software, Specific Programs. Medical Lab
Observer, Sept 1986, Oct 1986, Jan 1987, Feb 1987.
Siguel
E. Worth Switching to the New Microcomputers? Medical Lab Observer, Nov,
1987, p85-86.
Siguel
E. Selecting a Microcomputer. NSS Today, 1:14-15, Feb, 1985.
Siguel
E. Troubleshooting Data Transfer Problems. Medical Lab Observer,
17(7):87-90, July, 1985.
Siguel
E. How to become IBM PC Compatible. Medical Lab Observer, 17(11):97-98,
1985.
Siguel
E. Why the IBM PC? Medical Lab Observer, 17(10):97-98, 1985.
Siguel
E. Microcomputer Basics, Part I: Hardware. Pathologist 37:851-855, 1983;
Part II: Software. Pathologist 38:35-40, 1984; Part III: Selecting a
Microcomputer. Pathologist 38:112-116, 1984; Part IV: Using
Microcomputers in Pathology. Pathologist 38:181-184, 1984.
Siguel
E. The Advantages of Buying rather than Writing Software. Medical Lab
Observer, 16(8):95, Aug 1984.
Siguel E. Tips on buying Microcomputer
Hardware and Software. Med. Lab Obs., 16(9):113-117 Sept 1984.
Siguel E. World Wide Web and Home Pages: How to Use Them in a Lab. Two
Articles. MLO, 1995.
Unpublished reports
Siguel
E, Seubold F. Potential 10 year savings from HMO development Part 1, Health
Maint Org. Hearings before Subcom. on Public Health and Env.
Multivariate
regression analysis of the impact of the EEOC, OFCC and Justice Dept on employment
discrimination. OMB/ White House Task Force.
Reports
prepared for the National Institute on Drug Abuse dealing with planning and
evaluation of drug abuse programs and the epidemiology of drug abuse, such as:
Age at first use for heroin/marijuana users; Factors associated with success in
treatment; Incidence of heroin abuse according to the number of prior treatment
experiences, age, race, sex, SMSA; Tabulations of drugs of abuse by
social/demographic variables; A mathematical model of epidemics of drug abuse;
Budget, planning, and evaluations plans for the Institute.
Schaefer EJ, Moussa PB, Wilson PW, McGee D,
Siguel EN, Castelli WP. Coronary Artery Disease Risk Factors in Healthy
Octogenarians: Framingham Heart Study. J.Am.College of Nutr, 3:244, 1984
(Abstract).
BOOK REVIEWS
(selected)
Dixon WJ, ed. BMDP: Biomedical Computer
Programs. SCIENCE Books and Films
XI(3):117; Dec 1975.
Mizrahi A, Sullivan M. Calculus with Applications to Business and
Life Sciences. SCIENCE books &
films, 1976.
Dudley BAC. Mathematical and Biological Interrelations. SCIENCE Books and Films :15, 1979.
Arya JC, Lardner RW. Mathematics for the Biological
Sciences. SCIENCE Books & Films
XV(5):258, May 1980.
Jones DS, Sleeman BD. Differential Equations and Mathematical
Biology. George Allen and Unwin,
London, 1983. SCIENCE Books and Films 19:16,
Sept/Oct, 1983.
Metzger D. 22 Microcomputer Projects to Build, Use, and Learn. SCIENCE Books and Films 21(3):139, 1986.
|
All information on this website is copyrighted; see use and permission to reproduce. The information in this website is not medical advice, merely a general scientific discussion. See warnings & disclaimers. |
|
|
© 1998-2002 by Edward Siguel. All rights reserved |
modified 7/15/02 |