Research articles, presentations by Dr. Siguel

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In Dec94, Drs. Siguel and Lerman published a letter in the American J. of Clinical Nutrition stating that the USDA Food Pyramid should be revised because it fails to warn consumers that they need to eat more EFAs. In the Sept95 issues of the American J. of Clinical Nutrition, the USDA responds to Drs. Siguel and Lerman and they in turn reply to the USDA. The issues presented deal with the need for EFAs to supplement low fat foods and the risks of associated with eating diets low in EFAs. We discuss the need for EFAs to supplement low fat diets and the risks associated with eating diets low in EFAs. The following are copies of entire letters sent to the Am. J. Clinical Nutrition before editing.


At the American Society for Parenteral and Enteral Nutrition annual meeting January, 1996, ASPEN96, research was presented on the need for EFAs on patients with short bowel syndrome, inflammatory bowel disease, abnormal cholesterol (hyperlipidemia) and other conditions. Diagnoses and treatment were reviewed.

Patients with Crohn's disease or fat malabsorption or inflammatory bowel disease should read about recent research findings and publications by Dr. Siguel about EFA abnormalities in GI disease

In the journal Metabolism, 1996, Drs. Siguel and Lerman explain the EFA abnormalities found in patients with chronic gastrointestinal disease (such as Crohn's disease) and Cystic Fibrosis. The research shows that these patients often have severe EFA abnormalities that ought to be diagnosed and treated.


Symposium on Measurement of Essential Fatty Acids in Biological Tissues, including presentations from leading scientists and manufacturers. AOCS96


Designing EFA-Rich Foods for different population needs; see AOCS95 for more information.

Besides the increased risk for heart disease caused by a diet low in EFAs, low EFA diets increase the risk of a wide range of health problems, including decreased mental function, kidney disease, diabetes, high blood pressure, etc. After a period of several years on low fat diets, we anticipate a decrease in the population's plasma and adipose tissue levels of PUFAs, which must be corrected.

Elderly individuals and those who follow low calorie diets cannot obtain enough EFAs to meet cell needs using naturally occurring foods. These individuals must eat EFA-rich food supplements for the rest of their lives. Adults with significant EFA deficiencies must eat EFA supplements until their deficiencies are corrected. Growing children and pregnant women, who need to form a huge number of cell membranes, must eat EFA supplements to compensate for diets rich in SFAs and carbohydrates. EFA-rich supplements must also be designed for individuals with gastrointestinal disease and for those who cannot convert EFAs to EFA derivatives (either due to old age, disease, metabolic or genetic variability, or unknown disease).


At the AHA meeting in San Antonio in May, 1995, researchers presented data showing that current dietary treatments can only lower total cholesterol by up to 15%. However, one researcher presented a new nutritional therapy that can lower Total/HDL cholesterol by more than 50%. These data has been expanded and published in Lipids, diagnosis and treatment of high Total/HDL cholesterol.


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© 1998 Edward N. Siguel. All rights reserved

modified 9/17/98